Genipin Attachment of Conjugated Gold Nanoparticles to a Decellularized Tissue Scaffold

Decellularized Cartilage as a Scaffold for Tissue Engineered Cartilage

Effects of Genipin on Decellularized Porcine Cartilage

This research aims to develop an alternative method to osteochondral articular transfer using decellularized, crosslinked porcine osteochondral xenografts (OCXGs). Crosslinking collagenous tissue results in greater mechanical strength, more resistance to enzymatic degradation, and reduced immunogenicity. This study used genipin, a chemical substance from the Gardenia jasminoides Ellis fruit. Ge...

Dielectrophoresis of gold nanoparticles conjugated to DNA origami structures

DNA nanostructures are promising construction materials to bridge the gap between self-assembly of functional molecules and conventional top-down fabrication methods in nanotechnology. Their positioning onto specific locations of a microstructured substrate is an important task towards this aim. Here we study manipulation and positioning of pristine and of gold nanoparticle-conjugated tubular D...

Gold nanoparticles conjugated to benzoylmercaptoacetyltriglycine and L-cysteine methylester.

Benzoyl-protected mercaptoacetyltriglycine, a synthetic precursor used in the preparation of Technetium-99m-mercaptoacetyltriglycine, a radiopharmaceutical for renal tubular function and L-cysteine methylester, a small, non-zwitterionic amino acid derivative, were used as capping agents of gold nanoparticles obtained by borohydride reduction method. The capped gold nanoparticles composites were...

Genipin cross-linked electrospun chitosan-based nanofibrous mat as tissue engineering scaffold

Objective(s): To improve water stability of electrospun chitosan/ Polyethylene oxide (PEO) nanofibers, genipin, a biocompatible and nontoxic agent, was used to crosslink chitosan based nanofibers.  Materials and Methods: Different amounts of genipin were added to the chitosan/PEO solutions, chitosan/PEO weight ratio 90/10 in 80 % acetic acid, and the solutions were then electrospun to form nano...